J Anal Res Clin Med. 2016;4(2):115-121.
doi: 10.15171/jarcm.2016.019
  Abstract View: 611
  PDF Download: 474

Original Article

Predictive value of serum amylase level in outcome of multiple trauma patients

Arezu Nejabatian 1, Farzad Rahmani 2 * , Rozbeh Rajaei Ghafori 3, Samad Shams Vahdati 4, Parizad Varghayi 5, Hanieh Ebrahimi Bakhtavar 6

1 Assistant Professor, Emergency Medicine Research Team, Tabriz University of Medical Sciences, Tabriz, Iran
2 Assistant Professor, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3 Assistant Professor, Emergency Medicine Research Team, Tabriz University of Medical Sciences, Tabriz, Iran
4 Associate Professor, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5 Student of Medicine, Students Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
6 Emergency Medicine Research Team, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Introduction: The early detection of injury in multiple trauma patients can lead to decreased mortality, length of stay, and improved clinical status of the patient. It is shown that there is a relation between increased level of serum amylase and pancreatic injury in trauma patients. The aim of this study is to evaluate serum amylase level in hospital outcomes of patients with abdominal blunt trauma. Methods: This study was a cross-sectional survey that was conducted at the emergency room of Imam Reza (AS) Medical and Educational Center in Tabriz, Iran, during a year (April 2014-April 2015) on 101 patients with blunt abdominal trauma. Serum amylase levels were measured 6 hours after injury. The outcome of patients during hospitalization including the need for laparotomy and mortality were followed. Data were analyzed by SPSS software. P < 0.050 was considered significant. Results: A significant relationship between elevated serum amylase level by laparotomy and mortality was observed (P < 0.001). 15 patients had serum amylase higher than 100 U/L. All patients with abnormal serum amylase died. Conclusion: Determination of serum amylase level can be valuable in the prognosis of patients with blunt abdominal trauma, especially in determining mortality and proceed to laparotomy. However, studies with larger research community are required to investigate the precise role of amylase in the diagnosis and prognosis of patients with blunt abdominal trauma.
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Submitted: 27 Jan 2016
Accepted: 14 Feb 2016
First published online: 09 May 2016
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