J Anal Res Clin Med. 2018;6(1):52-54.
doi: 10.15171/jarcm.2018.008
  Abstract View: 313
  PDF Download: 433

Case Report

Subacute axonal motor polyneuropathy due to lead poisoning in an oral opium addict; a case report

Esmaeil Farzaneh 1, Afshin Habibzadeh 2 *

1 Department of Internal Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
2 Department of Internal Medicine, School of Medicine AND Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil, Iran


Introduction: Lead poisoning usually occurs in occupational situations, however, there are sometimes non-occupational toxicities and opium-related lead poisoning has been reported recently. Neuropathy due to lead poisoning can also occur. Case Report: In this study, a 43 year old man with a history of oral opium use with the complaint of progressive muscle weakness was reported. Muscle forces in the upper and lower limbs were 0/5 and 1/5, respectively. Serum lead level was 88.8 μg/dl. Electrodiagnostic studies were indicative of subacute moderate to severe axonal motor polyneuropathy. Following the treatment, the muscle force was improved and lead level was decreased. Conclusion: Motor neuropathy due to lead poisoning is a rare but possible complication. Due to the increased incidence of opium related lead toxicity in Ardabil, Iran, we recommend to consider lead poisoning as one of the possible differential diagnosis of peripheral neuropathy to initiate early and proper treatment.
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Submitted: 18 Oct 2017
Accepted: 16 Dec 2017
First published online: 17 Dec 2017
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